Systematic Reviews and Meta-Analysis on the low FODMAP diet in IBS

(Updated March 2022) by Lee Martin MSc RD

6 systematic reviews and meta analysis of the research evidence related to the Restriction Phase of the Low FODMAP Diet were completed between 2016 and 2018. In 2021 a network meta-analysis was published. Here we link to the research papers.

2016 Marsh et al Does a diet low in FODMAPs reduce symptoms associated with functional gastrointestinal disorders? A comprehensive systematic review and meta-analysis

Six RCTs and 16 non-randomized interventions were included in the analysis. 

2017 Altobelli et al Low-FODMAP Diet Improves Irritable Bowel Syndrome Symptoms: A Meta-Analysis

The aim of this study is to provide an update on the randomised control trials (RCTs) and cohort studies.

2017 Krogsgaard et al Systematic review: quality of trials on the symptomatic effects of the low FODMAP diet for irritable bowel syndrome

Pubmed and EMBASE were searched for randomised controlled trials (RCT s) reporting effect of the low FODMAP diet on IBS symptoms. The quality of trials was evaluated by estimating risk of bias and assessing trial methodology.

2017 Varjú et al Low fermentable oligosaccharides, disaccharides, monosaccharides and polyols (FODMAP) diet improves symptoms in adults suffering from irritable bowel syndrome (IBS) compared to standard IBS diet: A meta-analysis of clinical studies

Meta-analyze data on the therapeutic effect of a low-FODMAP diet on symptoms of IBS and quality of life and compare its effectiveness to a regular, standard IBS diet with high FODMAP content, using a common scoring system, the IBS Symptom Severity Score (IBS-SSS)

2018 Schumann et al Low fermentable, oligo-, di-, mono-saccharides and polyol diet in the treatment of irritable bowel syndrome: A systematic review and meta-analysis

Randomized controlled trials (RCTs) that compared LFD to other diets were included if they assessed symptoms of IBS or abdominal pain in patients with IBS.

2018 Dionne et al A Systematic Review and Meta-Analysis Evaluating the Efficacy of a Gluten-Free Diet and a Low FODMAPs Diet in Treating Symptoms of Irritable Bowel Syndrome

Systematic review and meta-analysis of randomized controlled trials (RCTs) examining the efficacy of the low FODMAP diet in IBS.

2021 Efficacy of a low-FODMAP diet in adult irritable bowel syndrome: a systematic review and meta-analysis

This review provides an updated overview of observational and intervention studies investigating the effect of a low-FODMAP (fermentable oligo-, di- and monosaccharides, and polyols) diet (LFD) on gastrointestinal (GI) symptoms, quality of life (QoL), nutritional adequacy, and gut microbiome in irritable bowel syndrome (IBS) patients.

2021 Black et al Efficacy of a low FODMAP diet in irritable bowel syndrome: systematic review and network meta-analysis